Molecular Genetics of Development & Birth Defects Faculty
The development of complex organs from a single fertilized cell is a complicated series of genetic, signaling, and cellular events that must be tightly coordinated in time and space. Our faculty are among the best in the world at discovering how these processes are regulated and occur. To do this, they use an array of genetically tractable model organisms, including the fruit fly drosopholia, zebrafish, and mice. Understanding how organisms develop has led to many new insights into how developmental defects in humans may also occur, including heart and lung defects, skin diseases, and Bardet-Biedl Syndrome to name a few. See also the Duke Center for Human Disease Modeling associated with the Department, which is part of this effort. Gifting and support for the important research conducted by faculty in this theme can be directed here.