Publications

Choi W. Y., Gemberling M., Wang J., Holdway J. E., Shen M. C., Karlstrom R. O., Poss K. D. (2013). In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration. Development 140, 660-666.


Gupta, V. and Poss, K. D. (2012).  Clonally dominant cardiomyocytes direct heart morphogenesis.  Nature 484, 479–484 .


Singh, S. P., Holdway, J. E., and Poss, K. D.  (2012).  Regeneration of amputated zebrafish fin rays by de novo osteoblasts.  Developmental Cell 22, 879-86.


Choi, W. Y. and Poss, K. D.  (2012).  Cardiac regeneration.  Current Topics in Developmental Biology 100, 319-344.

 

Yin, V. P., Lepilina, A., Smith, A., and Poss, K. D.  (2012).  Regulation of zebrafish heart regeneration by miR-133.  Developmental Biology 365, 319-327.


Nachtrab, G., Czerwinski, M., and Poss, K. D.  (2011).  Sexually dimorphic fin regeneration in zebrafish controlled by androgen/GSK3 signaling. Current Biology 21, 1912-1917.


Wang J, Panáková D, Kikuchi K, Holdway JE, Gemberling M, Burris JS, Singh SP, Dickson AL, Lin YF, Sabeh MK, Werdich AA, Yelon D, Macrae CA, Poss KD. (2011). The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion. Development 138(16), 3421-30.

Kikuchi, K., Gupta, V., Wang, J., Holdway, J. E., Wills, A. A., Fang, Y., and Poss, K. D.  (2011).  tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration. Development 138, 2895-2902.

Kikuchi, K., Holdway, J. E., Major, R. J., Blum, N., Dahn, R. D., Begemann, G., and Poss, K. D.  (2011). Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration. Developmental Cell 20, 397-404.

Shin, D., Lee, Y., Poss, K. D., and Stainier, D. Y. R.  (2011).  Restriction of hepatic competence by Fgf signaling. Development 138, 1339-1348.

Liu, J., Bressan, M., Hassel, D., Kikuchi, K., Poss, K.D., Mikawa, T. and Stainier, D.Y.R. (2010). A dual role for ErbB2 signaling in cardiac trabeculation. Development 137, 3867-3875.

Poss, K. D. (2010). Advances in understanding tissue regenerative capacity and mechanisms in animals. Nature Reviews Genetics 11, 710-722.

Lee, Y., Nachtrab, G., Klinsawat, P. W., Hami, D., and Poss, K. D. (2010). Ras controls melanocyte expansion during zebrafish fin stripe regeneration. Disease Models and Mechanisms 3, 496-503.

Yin, C., Kikuchi, K., Hochgreb, T., Poss, K. D., and Stainier, D. Y. R. (2010). Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. Developmental Cell 18, 973-984.

Gonzalez-Quevedo, R., Lee, Y., Poss, K. D., and Wilkinson, D. G. (2010). Neuronal regulation of the spatial patterning of neurogenesis. Developmental Cell 18, 136-147.

Kikuchi, K., Holdway, J.E., Werdich, A.A., Anderson, R.M., Fang, Y., Egnaczyk, G.F., Evans, T., MacRae, C.A., Stainier, D.Y.R., and Poss, K.D. (2010). Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes. Nature 464, 601-605.

Natchtrab, G., Poss, K.D. (2009). Genetic DISC-section of regeneration in Drosophila. Developmental Cell 16(6):777-8.

Lee, Y., Hami, D., De Val, S., Kagermeier-Schenkc, B., Wills, A.A., Black, B.L., Weidinger, G., Poss, K.D. (2009). Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins. Developmental Biology 331(2):270-80. Epub 2009 May 13.

Waxman, J. S., Keegan, B. R., Roberts, R. W., Poss, K. D., and Yelon, D. (2008). Hox5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish. Developmental Cell 15, 923-934.

Wills, A.A., Kidd, A.R., Lepilina, A., and Poss, K. D. (2008). Fgfs control homeostatic regeneration in adult zebrafish fins. Development 135, 3063-3070.

Yin, V. and Poss, K. D. (2008). New regulators of vertebrate appendage regeneration. Current Opinion in Genetics and Development 18, 381-386.

Marques, S., Lee, Y., Poss, K. D., and Yelon, D. (2008) Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart. Developmental Biology 321, 397-406.

Yin, V., Thompson, J. M., Thummel, R., Hyde, D., Hammond, S., and Poss, K. D. (2008). Fgf-dependent depletion of microRNA-133 promotes zebrafish appendage regeneration. Genes and Development 22, 728-733.

Wills A.A., Holdway J.E., Major R.J., Poss K.D. (2008). Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish. Development 135(1):183-92. Epub 2007 Nov 28.

Nechiporuk, A., Linbo, T., Poss, K.D., and Raible, D.W. (2007). Specification of epibranchial placodes in zebrafish. Development 134, 611-623.

Poss, K.D. (2006). Getting to the heart of regeneration in zebrafish. Semin Cell Dev Biol. 

Lepilina, A., Coon, A.N., Kikuchi, K., Holdway, J.E., Roberts, R.W., Burns, C.G., and Poss K.D., (2006). A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. Cell, Vol 127, 607-619.

Lee, Y., Grill, S., Sanchez, A., Murphy-Ryan, M., and Poss, K. D. (2005). Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration. Development 132, 5173-5183.

Poss KD. A zebrafish model of germ cell aneuploidy. Cell Cycle. 2004 Oct;3(10):1225-6. Epub 2004 Oct 13.

Poss, K. D., Nechiporuk, A., Stringer, K. F., Lee, C., and Keating, M. T. (2004). Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1. Genes and Development 18, 1527-1532.

Traver, D., Paw, B. H., Poss, K. D., Penberthy, W. T., Lin, S., and Zon, L. I. (2003). Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature Immunology 4, 1238-1246.

Poss, K. D., Keating, M. T., and Nechiporuk, A. (2003). Tales of regeneration in zebrafish. Developmental Dynamics 226, 202-210.

Nechiporuk, A., Poss, K. D., Johnson, S. L., and Keating, M. T. (2003). Positional cloning of a temperature-sensitive mutant emmental reveals a role for Sly1 during cell proliferation in zebrafish fin regeneration. Developmental Biology 258, 291-306.

Poss, K. D., Wilson, L. G., and Keating, M. T. Heart regeneration in zebrafish. (2002). Science 298, 2188-2190.

Poss, K. D., Nechiporuk, A., Hillam, A. M., Johnson, S. L., and Keating, M. T. (2002). Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration. Development 129, 5141-5149.

Poss, K. D., Shen, J., Nechiporuk, A., McMahon, G., Thisse, B., Thisse, C., and Keating, M. T. (2000). Roles for Fgf signaling during zebrafish fin regeneration. Developmental Biology 222, 347-358.

Poss, K. D., Shen, J., and Keating, M. T. (2000). Induction of lef1 during zebrafish fin regeneration. Developmental Dynamics 219, 282-286.