Harold P. Erickson, Publications 1996 and earlier

Settles, D.L., R.A. Cihak, and H.P. Erickson. 1996. Tenascin-C expression in dystrophin-related muscular dystrophy. Muscle Nerve. 19:147-154.

Erickson, H.P., D.W. Taylor, K.A. Taylor, and D. Bramhill. 1996. Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers. Proc.Natl.Acad.Sci.USA. 93:519-523.

Leahy, D.J., I. Aukhil, and H.P. Erickson. 1996. 2.0 Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell. 84:155-164.

Li, F.G., H.P. Erickson, J.A. James, K.L. Moore, R.D. Cummings, and R.P. McEver. 1996. Visualization of P-selectin glycoprotein ligand-1 as a highly extended molecule and mapping of protein epitopes for monoclonal antibodies. J.Biol.Chem. 271:6342-6348.

Chung, C.Y., J.E. Murphy-Ullrich, and H.P. Erickson. 1996. Mitogenesis, cell migration and loss of focal adhesion induced by tenascin-C interacting with its cell surface receptor, annexin II. Mol.Biol.Cell. 7:883-892.

LeMosy, E.K., V.A. Lightner, and H.P. Erickson. 1996. Structural analysis of a human glial variant laminin. Exp.Cell Res. 227:80-88.

Savarese, J.J., H. Erickson, and S.P. Scully. 1996. Articular chondrocyte tenascin-C production and assembly into de novo extracellular matrix. J.Orthop.Res. 14:273-281.

Erickson, H.P., and D. Stoffler. 1996. Protofilaments and rings, two conformations of the tubulin family conserved from bacterial FtsZ to alpha/beta and gamma tubulin. J.Cell Biol. 135:5-8.

Erickson, H.P., and G. Briscoe. 1995. Tenascin, laminin and fibronectin produced by cultured cells. In Extracellular matrix: a practical approach. M.A. Haralson and J.R. Hassell, editors. Oxford University Press, Oxford. 187-198.

Steindler, D.A., D. Settles, H.P. Erickson, E.D. Laywell, A. Yoshiki, A. Faissner, and M. Kusakabe. 1995. Tenascin knockout mice: Barrels, boundary molecules, and glial scars. J.Neurosci. 15:1971-1983.

Burns, C.G., D.A. Larochelle, H. Erickson, M. Reedy, and A. De Lozanne. 1995. Single-headed myosin II acts as a dominant negative mutation in Dictyostelium. Proc.Natl.Acad.Sci.USA. 92:8244-8248.

Erickson, H.P. 1995. FtsZ, a prokaryotic homolog of tubulin? Cell. 80:367-370.

Jones, P.L., N. Boudreau, C.A. Myers, H.P. Erickson, and M.J. Bissell. 1995. Tenascin-C inhibits extracellular matrix-dependent gene expression in mammary epithelial cells. Localization of active regions using recombinant tenascin fragments. J.Cell Sci. 108:519-527.

Qiao, T., B.K. Maddox, and H.P. Erickson. 1995. A novel alternative splice domain in zebrafish tenascin-C. Gene. 156:307-308.

Chung, C.Y., L. Zardi, and H.P. Erickson. 1995. Binding of tenascin-C to soluble fibronectin and matrix fibrils. J.Biol.Chem. 270:29012-29017.

Erickson, H.P. 1994. Evolution of the tenascin family * implications for function of the C*terminal fibrinogen-like domain. Persp.Dev.Neurobiol. 2:9-19.

Rettig, W.J., H.P. Erickson, A.P. Albino, and P. Garin-Chesa. 1994. Induction of human tenascin (neuronectin) by growth factors and cytokines: Cell type-specific signals and signalling pathways. J.Cell Sci. 107:487-497.

Young, S.L., L.-Y. Chang, and H.P. Erickson. 1994. Tenascin-C in rat lung: Distribution, ontogeny and role in branching morphogenesis. Dev.Biol. 161:615-625.

Leahy, D.J., H.P. Erickson, I. Aukhil, P. Joshi, and W.A. Hendrickson. 1994. Crystallization of a fragment of human fibronectin: introduction of methionine by site-directed mutagenesis to allow phasing via selenomethionine. Proteins. 19:48-54.

Julian, J., R. Chiquet-Ehrismann, H.P. Erickson, and D.D. Carson. 1994. Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion. Development. 120:661-671.

Chung, C.Y., and H.P. Erickson. 1994. Cell surface annexin II is a high affinity receptor for the alternatively spliced segment of tenascin-C. J.Cell Biol. 126:539-548.

Erickson, H.P. 1994. Reversible unfolding of FN3 domains provides the structural basis for stretch and elasticity of titin and fibronectin. Proc.Natl.Acad.Sci.USA. 91:10114-10118.

Sadhu, C., B. Lipsky, H.P. Erickson, J. Hayflick, K.O. Dick, W.M. Gallatin, and D.E. Staunton. 1994. LFA-1 binding site in ICAM-3 contains a conserved motif and non-contiguous amino acids. Cell Adhesion & Communication. 2:429-440.

Aukhil, I., P. Joshi, Y. Yan, and H.P. Erickson. 1993. Cell- and heparin-binding domains of the hexabrachion arm identified by tenascin expression proteins. J.Biol.Chem. 268:2542-2553.

Chandra, R., E.D. Salmon, H.P. Erickson, A. Lockhart, and S.A. Endow. 1993. Functional domains of the Drosophila ncd microtubule motor protein. J.Biol.Chem. 268:9005-9013.

Ushiyama, S., T.M. Laue, K.L. Moore, H.P. Erickson, and R.P. McEver. 1993. Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P selectin. J.Biol.Chem. 268:15229-15237.

Erickson, H.P. 1993. Gene knockouts of c-src, TGF-beta1, and tenascin suggest superfluous, non functional expression of proteins. J.Cell Biol. 120:1079-1081.

Perides, G., H.P. Erickson, F. Rahemtulla, and A. Bignami. 1993. Colocalization of tenascin with versican, a hyaluronate-binding chondroitin sulfate proteoglycan. Anat.Embryol.(Berl). 188:467 479.

Joshi, P., C.-Y. Chung, I. Aukhil, and H.P. Erickson. 1993. Endothelial cells adhere to the RGD domain and the fibrinogen-like terminal knob of tenascin. J.Cell Sci. 106:389-400.

Erickson, H.P. 1993. Tenascin-C, tenascin-R and tenascin-X: A family of talented proteins in search of functions. Curr.Opin.Cell Biol. 5:869-876.

Vollmer, G., V.A. Lightner, C.A. Carter, G.P. Siegal, H.P. Erickson, R. Knuppen, and D.G. Kaufman. 1993. Localization of tenascin in uterine sarcomas and partially transformed endometrial stromal cells. Pathobiology. 61:67-76.

Northrup, S.H., and H.P. Erickson. 1992. Kinetics of protein-protein association explained by Brownian dynamics computer simulation. Proc.Natl.Acad.Sci.USA. 89:3338-3342.

Erickson, H.P., and E.T. O'Brien. 1992. Microtubule dynamic instability and GTP hydrolysis. Annu.Rev.Biophys.Struct.Biol. 21:145-166.

LeMosy, E.K., H.P. Erickson, W.F. Beyer, Jr., J.T. Radek, J.-M. Jeong, S.N.P. Murthy, and L. Lorand. 1992. Visualization of purified fibronectin-transglutaminase complexes. J.Biol.Chem. 267:7880-7885.

Leahy, D.J., W.A. Hendrickson, I. Aukhil, and H.P. Erickson. 1992. Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. Science. 258:987-991.

Schaefer, E.M., H.P. Erickson, M. Feterwisch, A. Wollmer, and L. Ellis. 1992. Structural organization of the human insulin receptor ectodomain. J.Biol.Chem. 267:23393-23402.

Voter, W.A., E.T. O'Brien, and H.P. Erickson. 1991. Dilution-induced disassembly of microtubules: Relation to dynamic instability and the GTP cap. Cell Motil.Cytoskeleton. 18:55-62.

Murphy-Ullrich, J.E., V.A. Lightner, I. Aukhil, Y.Z. Yan, H.P. Erickson, and M. Höök. 1991. Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin. J.Cell Biol. 115:1127-1136.

Abbott, L.A., S.M. Lester, and C.A. Erickson. 1991. Changes in mesenchymal cell-shape, matrix collagen and tenascin accompany bud formation in the early chick lung. Anat.Embryol. 183:299 311.

Lightner, V.A., and H.P. Erickson. 1990. Binding of hexabrachion (tenascin) to the extracellular matrix and substratum and its effect on cell adhesion. J.Cell Sci. 95:263-277.

Aukhil, I., C.A. Slemp, V.A. Lightner, K. Nishimura, G. Briscoe, and H.P. Erickson. 1990. Purification of hexabrachion (tenascin) from cell culture conditioned medium, and separation from a cell adhesion factor. Matrix. 10:98-111.

Lightner, V.A., C.A. Slemp, and H.P. Erickson. 1990. Localization and quantitation of hexabrachion (tenascin) in skin, embryonic brain, tumors, and plasma. Ann.N.Y.Acad.Sci. 580:260-275.

Neely, M.D., H.P. Erickson, and K. Boekelheide. 1990. HMW-2, the Sertoli cell cytoplasmic dynein from rat testis, is a dimer composed of nearly identical subunits. J.Biol.Chem. 265:8691 8698.

Staunton, D.E., M.L. Dustin, H.P. Erickson, and T.A. Springer. 1990. The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus. Cell. 61:243-254.

O'Brien, E.T., E.D. Salmon, R.A. Walker, and H.P. Erickson. 1990. The effects of magnesium on dynamic instability of individual microtubules. Biochemistry. 29:6648-6656.

Becker, J.W., H.P. Erickson, S. Hoffman, B.A. Cunningham, and G.M. Edelman. 1989. Topology of cell adhesion molecules. Proc.Natl.Acad.Sci.USA. 86:1088-1092.

Anderson, K., F.A. Lai, Q.L. Liu, E. Rousseau, H.P. Erickson, and G. Meissner. 1989. Structural and functional characterization of the purified cardiac ryanodine receptor-Ca release channel complex. J.Biol.Chem. 264:1329-1335.

Kirshner, N., J.J. Corcoran, and H.P. Erickson. 1989. Synthesis of alpha-2 macroglobulin by bovine adrenal cortical cell cultures. Am.J.Physiol.(Cell Physiol.). 256:C779-C785.

Carrell, N.A., H.P. Erickson, and J. McDonagh. 1989. Electron microscopy and hydrodynamic properties of factor XIII subunits. J.Biol.Chem. 264:551-556.

O'Brien, E.T., and H.P. Erickson. 1989. Assembly of pure tubulin in the absence of free GTP: Effect of magnesium, glycerol, ATP, and the nonhydrolyzable GTP analogues. Biochemistry. 28:1413-1422.

Erickson, H.P. 1989. Cooperativity in protein-protein association: the structure and stability of the actin filament. J.Mol.Biol. 206:465-474.

Jones, A.M., and H.P. Erickson. 1989. Domain structure of phytochrome from avena sativa visualized by electron microscopy. Photochemistry and Photobiology. 49:479-483.

Lightner, V.A., C. Pegram, D. Bigner, and H.P. Erickson. 1989. Monoclonal antibody 127 recognizes a subpopulation of chicken hexabrachion/tenascin. In Cytoskeletal and extracellular matrix proteins. U. Aebi and J. Engel, editors. Springer-Verlag, Berlin. 114-116.

Taylor, H.C., V.A. Lightner, W.F. Beyer, Jr., D. McCaslin, G. Briscoe, and H.P. Erickson. 1989. Biochemical and structural studies of tenascin/hexabrachion proteins. J.Cell.Biochem. 41:71-90.

Lightner, V.A., F. Gumkowski, D.D. Bigner, and H.P. Erickson. 1989. Tenascin/hexabrachion in human skin: biochemical identification and localization by light and electron microscopy. J.Cell Biol. 108:2483-2494.

Erickson, H.P., and M.A. Bourdon. 1989. Tenascin: an extracellular matrix protein prominent in specialized embryonic tissues and tumors. Annu.Rev.Cell Biol. 5:71-92.

Lotz, M.M., C.A. Burdsal, H.P. Erickson, and D.R. McClay. 1989. Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response. J.Cell Biol. 109:1795-1805.

O'Keefe, E.J., H.P. Erickson, and V. Bennett. 1989. Desmoplakin I and desmoplakin II. Purification and characterization. J.Biol.Chem. 264:8310-8318.

Mukherjee, S., H.P. Erickson, and D. Bastia. 1988. Detection of DNA looping due to simultaneous interaction of a DNA-binding protein with two spatially separated binding sites on DNA. Proc.Natl.Acad.Sci.USA. 85:6287-6291.

Mukherjee, S., H.P. Erickson, and D. Bastia. 1988. Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein. Cell. 52:375-383.

Lai, F.A., H.P. Erickson, E. Rousseau, Q.Y. Liu, and G. Meissner. 1988. Purification and reconstitution of the calcium release channel from skeletal muscle. Nature. 331:315-319.

Alliegro, M.C., C.A. Ettensohn, C.A. Burdsal, H.P. Erickson, and D.R. McClay. 1988. Echinonectin: a new embryonic substrate adhesion protein. J.Cell Biol. 107:2319-2327.

Walker, R.A., E.T. O'Brien, N.K. Pryer, M.F. Soboeiro, W.A. Voter, H.P. Erickson, and E.D. Salmon. 1988. Dynamic instability of individual microtubules analyzed by video light microscopy: Rate constants and transition frequencies. J.Cell Biol. 107:1437-1448.

Erickson, H.P., and V.A. Lightner. 1988. Hexabrachion protein (tenascin, cytotactin, brachionectin) in connective tissues, embryonic brain, and tumors. In Advances in Cell Biology, vol. 2. K.R. Miller, editor. JAI Press, London. 55-90.

Banerjea, A.C., K.A. Brechling, H.P. Erickson, D.J. Pickup, and W.K. Joklik. 1988. High-level synthesis of biologically active reovirus Protein sigma-1 in a mammalian expression vector system. Virology. 167:601-612.

Lai, F.A., H.P. Erickson, B.A. Block, and G. Meissner. 1987. Evidence for a junctional feet ryanodine receptor complex from sarcoplasmic reticulum. Biochem.Biophys.Res.Commun. 143:704-709.

Erickson, H.P., and H.C. Taylor. 1987. Hexabrachion proteins in embryonic chicken tissues and human tumors. J.Cell Biol. 105:1387-1394.

O'Brien, E.T., W.A. Voter, and H.P. Erickson. 1987. GTP hydrolysis during microtubule assembly. Biochemistry. 26:4148-4156.

Voter, W.A., E.T. O'Brien, and H.P. Erickson. 1987. A calculation of the GTP cap size based on observed frequencies of microtubule catastrophe. Biophys.J. 51:214a.

Voter, W.A., C. Lucaveche, and H.P. Erickson. 1986. Concentration of protein in fibrin fibers and fibrinogen polymers determined by refractive index matching. Biopolymers. 25:2375-2384.

Voter, W.A., C. Lucaveche, A.E. Blaurock, and H.P. Erickson. 1986. Lateral packing of protofibrils in fibrin fibers and fibrinogen polymers. Biopolymers. 25:2359-2373.

Fretto, L.J., W.E. Fowler, D.R. McCaslin, H.P. Erickson, and P.A. McKee. 1986. Substructure of human von Willebrand factor. Proteolysis by V8 and characterization of two functional domains. J.Biol.Chem. 261:15679-15689.

Erickson, H.P. 1986. Nucleosome structure [letter]. Science. 233:1429-1431.

Erickson, H.P., and W.A. Voter. 1986. Nucleation of microtubule assembly. Experimental kinetics, computer fitting of models, and observations on tubulin rings. Ann.N.Y.Acad.Sci. 466:552-565.

Milam, L.M., and H.P. Erickson. 1985. A structural comparison of tryptic fragments of three types of intermediate filaments. J.Ultrastruct.Res. 90:251-260.

Fowler, W.E., L.J. Fretto, K.K. Hamilton, H.P. Erickson, and P.A. McKee. 1985. Substructure of human von Willebrand factor. Journal of Clinical Investigation. 76:1491-1500.

Carrell, N.A., L.A. Fitzgerald, B. Steiner, H.P. Erickson, and D.R. Phillips. 1985. Structure of human platelet membrane glycoproteins IIb and IIIa as determined by electron microscopy. J.Biol.Chem. 260:1743-1749.

Erickson, H.P. 1985. Structure of fibronectin seen by electron microscopy. In "Plasma fibronectin". J. McDonagh, editor. Marcel Dekker, New York. 31-51.

Milam, L.M., and H.P. Erickson. 1984. Structural characteristics of the desmin protofilament. J.Ultrastruct.Res. 89:179-186.

Erickson, H.P., and J.L. Iglesias. 1984. A six-armed oligomer isolated from cell surface fibronectin preparations. Nature. 311:267-269.

Voter, W.A., and H.P. Erickson. 1984. The kinetics of microtubule assembly. Evidence for a two stage nucleation mechanism. J.Biol.Chem. 259:10430-10438.

Erickson, H.P., and N.A. Carrell. 1983. Fibronectin in extended and compact conformations. Electron microscopy and sedimentation analysis. J.Biol.Chem. 258:14539-14544.

Erickson, H.P., and W.E. Fowler. 1983. Electron microscopy of fibrinogen, its plasmic fragments and small polymers. Ann.N.Y.Acad.Sci. 408:146-163.

Brown, H.R., and H.P. Erickson. 1983. Assembly of proteolytically cleaved tubulin. Arch.Biochem.Biophys. 220:46-51.

Ohmori, K., L.J. Fretto, R.L. Harrison, M.E. Switzer, H.P. Erickson, and P.A. McKee. 1982. Electron microscopy of human factor VIII/Von Willebrand glycoprotein: effect of reducing reagents on structure and function. J.Cell Biol. 95:632-640.

Voter, W.A., and H.P. Erickson. 1982. Electron microscopy of MAP 2 (microtubule-associated protein 2). J.Ultrastruct.Res. 80:374-382.

Milam, L.M., and H.P. Erickson. 1982. Visualization of a 21-nm axial periodicity in shadowed keratin filaments and neurofilaments. J.Cell Biol. 94:592-596.

Erickson, H.P. 1982. Electron microscopy vs. hydrodynamics for determining the shape of protein molecules. Biophys.J. 37:96a.

Erickson, H.P., N.A. Carrell, and J. McDonagh. 1981. Fibronectin molecule visualized in electron microscopy: a long, thin, flexible strand. J.Cell Biol. 91:673-678.

Fowler, W.E., R.R. Hantgan, J. Hermans, and H.P. Erickson. 1981. Structure of the fibrin protofibril. Proc.Natl.Acad.Sci.USA. 78:4872-4876.

Hesterberg, L.K., J.C. Lee, and H.P. Erickson. 1981. Structural properties of an active form of rabbit muscle phosphofructokinase. J.Biol.Chem. 256:9724-9730.

Erickson, H.P., and D. Pantaloni. 1981. The role of subunit entropy in cooperative assembly. Nucleation of microtubules and other two-dimensional polymers. Biophys.J. 34:293-309.

Fowler, W.E., H.P. Erickson, R.R. Hantgan, J. McDonagh, and J. Hermans. 1981. Cross-linked fibrinogen dimers demonstrate a feature of the molecular packing in fibrin fibers. Science. 211:287-289.

Erickson, H.P. 1980. Thermodynamic and kinetic aspects of assembly. Prog.Clin.Biol.Res. 40:327-330.

Fowler, W.E., L.J. Fretto, H.P. Erickson, and P.A. McKee. 1980. Electron microsocpy of plasmic fragments of human fibrinogen as related to trinodular structure of the intact molecule. Journal of Clinical Investigation. 66:50-56.

Hantgan, R., W. Fowler, H.P. Erickson, and J. Hermans. 1980. Fibrin assembly: a comparison of electron microscopic and light scattering results. Thromb.Haemost. 44:119-124.

Erickson, H.P. 1980. Self-assembly and nucleation of a two dimensional array of protein subunits. In "Electron microscopy at molecular dimensions". W. Baumeister and W. Vogell, editors. Springer Verlag. 309-317.

Erickson, H.P., and D. Pantaloni. 1980. Nucleation of microtubule assembly-a simple model based on thermodynamics. In "Microtubules and microtubule inhibitors 1980". M. DeBrabander and J. deMay, editors. Elsevier. 119-132.

Fowler, W.E., and H.P. Erickson. 1979. Trinodular structure of fibrinogen. Confirmation by both shadowing and negative stain electron microscopy. J.Mol.Biol. 134:241-249.

Voter, W.A., and H.P. Erickson. 1979. Tubulin rings: curved filaments with limited flexibility and two modes of association. J.Supramol.Struct. 10:419-431.

Erickson, H.P., W.A. Voter, and K. Leonard. 1978. Image reconstruction in electron microscopy: enhancement of periodic structure by optical filtering. Methods Enzymol. 49:39-63.

Erickson, H.P. 1978. The structure of one and two dimensional polymers of tubulin and their role in nucleation of microtubule assembly. In "Electron Microscopy 1978". M.S.o. Canada, editor. University of Toronto, Toronto. 483-494.

David-Pfeuty, T., H.P. Erickson, and D. Pantaloni. 1977. Guanosinetriphosphatase activity of tubulin associated with microtubule assembly. Proc.Natl.Acad.Sci.USA. 74:5372-5376.

Erickson, H.P., and B. Scott. 1977. Microtubule assembly in DEAE dextran: effect of charge density and MW of the polycation. Biophys.J. 17:274a.

Erickson, H.P., and W.A. Voter. 1976. Polycation-induced assembly of purified tubulin. Proc.Natl.Acad.Sci.USA. 73:2813-2817.

Erickson, H.P. 1976. Facilitation of microtubule assembly by polycations. In "Cell Motility". R. Goldman, T. Pollard, and J. Rosembaum, editors. Cold Spring Harbor Laboratory. 1069-1080.

Erickson, H.P. 1975. The structure and assembly of microtubules. Ann.N.Y.Acad.Sci. 253:60-77.

Erickson, H.P. 1975. Negatively stained vinblastine aggregates. Ann.N.Y.Acad.Sci. 253:51-52.

Erickson, H.P. 1974. Assembly of microtubules from preformed, ring-shaped protofilaments and 6-S tubulin. J.Supramol.Struct. 2:393-411.

Erickson, H.P. 1974. Microtubule surface lattice and subunit structure and observations on reassembly. J.Cell Biol. 60:153-167.

Voter, W.A., and H.P. Erickson. 1974. An experimental study of deviations from the linear transfer function. In Proceedings of the Electron Microscopy Society of America, 32nd Annual Meeting. C.J. Arceneaux, editor. Claitor's Publishing Division. 400-401.

Erickson, H.P. 1973. The fourier transform of an electron micrograph - first and second order theory of image formation. In "Advances in optical and electron microscopy". R. Barer and V.E. Cosslett, editors. Academic Press. 163-199.

Erickson, H.P., and A. Klug. 1971. Measurement and compensation of defocussing and aberrations by fourier processing of electron micrographs. Philos.Trans.R.Soc.Lond.[Biol.]. 261:105-118.

Beer, M., P. Bartl, T. Koller, and H.P. Erickson. 1971. Electron Microscopy of nucleic acids. In Methods in cancer research. H. Busch, editor. Academic Press. 283-309.

Erickson, H.P., and A. Klug. 1970. The fourier transform of an electron micrograph: effects of defocussing and aberrations, and implications for the use of underfocus contrast enhancement. Berichte der Bunsen-Gesellschaft fur Physikalische Chemie. 74:1129-1137.

Erickson, H.P., and M. Beer. 1968. Visibility of single nucleic acid molecules and implications for the study of nucleic acid sequence. In Electron Microscopy 1968, Vol. 2, Roma. 87.

Blattner, F., and H.P. Erickson. 1967. Rapid nucleotide separation by chromatography on cation exchange columns. Anal.Biochem. 18:220-227.

Erickson, H.P., and M. Beer. 1967. Electron microscopic study of base sequence in nucleic acids VI: preparation of RNA with marked GMP nucleotides. Biochemistry. 6:2694-2701.