| Fall
2009 |
Spring 2010 |
| CBI 251 Molecular Cell Biology (MWF 10:30-11:40am; Lew/Nicchitta, 001 MSRB. 4 units).
This course covers a broad range of topics in modern cell biology, with an emphasis
on reading and discussion of primary research papers. The classes typically begin
with a background presentation by the professor, followed by class discussion
of the papers. CBI 280 Special Topics in Cell Biology (Caron; Location TBA. 1 unit). Preparation and presentation of seminars to students and faculty based on current papers covering topics of broad interest to cell biology and physiology. Required of Department of Cell Biology students. BIO/CBI 282/283 (282 Mechanisms of Development/ 283 Developmental Genetics) (Tu, Th, 10:55 a.m.–12:10 p.m., 384 Nanaline Duke, Klingensmith, 2 unit each). These two courses are taught sequentially as two half-semester minicourses. Mechanisms of development will introduce basic concepts of cell specification, morphogenesis, induction, and other mechanisms that enable cells, tissues and organs to assemble the animal. Developmental genetics will focus on genetic approaches to solve mechanistic problems of development using model organisms, mainly Drosophila, mouse and zebrafish. |
CBI
203 Introduction to Physiology (MWF 8:45–9:35 am, Jakoi/Wright,
143 Jones Bldg. 3 units, first half-semester.) The objective of the
course is to provide an introduction to Human Physiology with information
about how the basic organ systems (lung, cardiovascular, gastrointestinal,
endocrine, and kidney) of the body work and how the systems are coordinated. CBI 206. Physiology and Medicine of Extreme Environments. (T-Th 2:50-4:05; Vann, Freiberger, Pollock; CR11, Room 0585 Duke South. Credit: 3 units. Enrollment: max 12.) Advanced topics in the physiology and medicine of ambient pressure, immersion, gravity, temperature, and gas composition. Environments considered include: diving and hyperbaric medicine; hot/cold terrestrial and water operations; microgravity and high-g acceleration; high altitude: and space. Basic mechanisms and medical management of: decompression sickness; altitude sickness; hypothermia and hyperthermia; hypoxia; carbon monoxide poisoning; and oxygen toxicity. Practical applications: pressure vessel design and operation; life support equipment; cardiorespiratory physiology measurements at low and high pressure; simulated dive and flight (optional). Prerequisites: Human anatomy and physiology. For more information please contact Dr. Vann at 684-3305 or vann0001@mc.duke.edu. CBI/MCB 208 Stem Cell Biology (TuTh 10:05–11:20 am; Reya, Hogan; 384 Nanaline. 3 units.) Lecture/discussion format designed for first-year graduate students to learn the fundamentals of stem cell biology and to gain familiarity with current research in the field. Prerequisites: undergraduate level cell biology, molecular biology and genetics. CBI 241 Cell Biological Processes (Minicourse, 1st half-semester MW 8:30–9:45 am; Schachat; 465 Sands; 2 units). This course is a graduate level introduction to the molecular mechanisms that underlie cellular processes and the experimental techniques used in cell biological research. The lectures will address the processes that cells use to organize themselves into tissues and organs, communicate through second messengers, generate specialized compartments for protein segregation, process information, move and differentiate. Preparatory for CBI 251 and CBI 280. CBI 243/ENV 243 Respiratory Proteins and the Environment This course will be taught in Beaufort at the Duke Marine Lab. It will be taught in block C (March 15 - April 9, Time TBA; C. Bonaventura) Structure, function and evolution of copper and iron based respiratory proteins in response to environmental oxygen levels and physiological needs. Lectures and readings on the balance between pathways for metabolic oxygen utilization and alternative disease-causing pathways involving oxidative and nitrosative reactions. Interactive molecular graphics and student presentations supplement text and lectures. Covers molecular adaptations, circulation, allostery, reaction kinetics and thermodynamics, reactive oxygen and nitrogen species, gene expression, blood pathogens, malaria, sickle cell anemia. Prerequisites: organic chemistry or consent of instructor. CBI 280 Seminar (Tu 4:25–5:25 pm; Capel; Room TBA. 1 unit.) Preparation and presentation of seminars to students and faculty based on current papers covering topics of broad interest to cell biology and physiology. Required of Department of Cell Biology CBI 296 Developmental Biology Colloquium (M 5:00-600 pm W 4:00–6:00 pm; Klingensmith/McClay. 3 units.) This course covers a broad range of problems in developmental biology based on prominent developmental biologists who are invited to speak at Duke University during that particular semester and participate in discussions with the class. CBI/MCB/BIOCHEM 417 Cellular Signaling (MWF 8:45-9:35 am; Caron; 147 Nanaline. 3 units.) Mechanisms of signaling at the cellular level, including ligand/receptor interactions and secondary messenger ystems. Some lectures stress the clinical correlation of the basic course concepts. |