Movie Gallery

   
     
   
     
   
     
   
     
   
     
   
     
   
     
   

These movies require that QuickTime movie player is installed on your computer.

 
3D Reconstruction of Brain

Movie    ( 4.11 MB)

3D reconstruction of the brain – MRI imaging of a wildtype mouse brain.

Movie    ( 0.475 MB)

Example of leading edge extension of lamellipodia. Extension of the lamellipodia depends on dynamic actin remodeling. This movie is of a melanoma cell line infected with GFP-actin adenovirus.

Movie    ( 2.37 MB)

Melanoma cells migrating and dividing over time. This movie is imaged in DIC overnight.

Movie    ( 0.546 MB)

Low density culturing of hippocampal neurons allows us to effectively image dynamic movement. Motility of the growth cones at the tips of the neurites can be seen.

Movie    ( 0.744 MB)

Example of a growth cone visualized with soluble GFP. Extension and retraction of the lamellipodia is readily apparent.

Movie    (0.535 MB)

Another example of a hippocampal growth cone imaged in 3D over time.

Movie    ( 1.17 MB)

Mature hippocampal neurons expressing YFP-actin. This movie shows the dynamic nature of dendritic spines, which are also actin rich structures.

Movie    ( 1.15 MB)

Example of the Rotorod test. This is a behavioral test of motor function where we measure the latency of mice to fall of an elevated rotating rod. Mice with balance and coordination defects will fall off sooner than wild type mice.

Movie    ( 0.441 MB)

This is a movie of the Morris Water Maze test of learning and memory. Movie shows both the visible and hidden platform training sessions.

Movie    ( 1.03 MB)

The Balance Beam test. This behavioral test also measures balance and coordination. Movement along the beam is quantitated using video tracking of the mouse during testing.

Movie    ( 0.995 MB)

Example of Novel Object Recognition test of learning and memory. Ability of mice to learn and remember novel objects from one session to the next is quantitated.