Selected
Publications
Kunzmann, S. J.R. Wright,
W. Steinhilber, B. W. Kramer, K. Blaser, C.P. Speer,
C. Schmidt-Weber. TGF-{beta}1
in SP-A preparations influences immune suppressive
properties of SP-A on human CD4+ T lymphocytes. Am
J Physiol Lung Cell Mol Physiol, In Press, 2006.
Williams, K.L. , J.D.
Lich, J.A. Duncan, W. Reed, P. Rallabhandi, C. Moore,
S. Kurtz, V.M. Coffield,
M.A. Accavitti-Loper, L. Su, , S.N. Vogel, M. Braunstein
and J.P.-Y. Ting . The CATERPILLER
protein monarch-1 is an antagonist of toll-like receptor-,
tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced
pro-inflammatory signals. Journal of Biological Chemistry. 2005 280(48):
39914-24.
Wright,
JR. Immunoregulatory Functions of Surfactant Proteins.
Nature Reviews Immunology: 2005; 5:58-68. -PDF-
Kannan, T.R., D. Provenzano,
J.R. Wright, and J.B. Baseman, Identification and characterization
of human surfactant protein-A binding protein of Mycoplasma
pneumoniae. Infection & Immunity 2005 73:2828-2834.
Zaas D, Duncan M, Li G, Wright JR, Abraham SN. Pseudomonas
invasion of type I pneumocytes is dependent on the
expression and phosphorylation of caveolin-2. J Biol
Chem. 2005: 280:4864-4872. -PDF-
Alcorn JF, Wright JR. Degradation of pulmonary surfactant
protein D by Pseudomonas aeruginosa elastase abrogates
innate immune function. J Biol Chem. 2004 Jul 16;279(29):30871-9. -PDF-
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Current
Projects
Bethany Brown (Graduate
Student): Investigating role of caveolin and surfactant
in infectivity of respiratory syncytial virus.
Jen
Coneski (Graduate Student): Investigating regulation
of T-cell function by surfactant.
Kathy Evans (Research
Analyst): Determining cell specific responses of
immune cells to SP-A and SP-D.
Steven Giles, Ph.D.. (Post-doctoral Fellow): Studying
the role of surfactant in regulating dendritic cell
responses to Cryptococcus neoformans.
Scarlett
Guenes-Boyer (Graduate Student): Studying interactions
of surfactant with Cryptococcus
neoformans.
Rachel Lovingood (Graduate Student): Investigating
surfactant and viral immunity.
Bernice
Lo (Graduate Student): Studying role of lung cells
in antigen presentation.
Amy Pastva, Ph.D. (Post-doctoral Fellow):
Studying role of regulation of dendritic cells and
eosinophils by surfactant proteins.
Mike Reidy, M.D.
(Asst. Professor): Evaluating regulation of lung inflammation
by SP-A.
DeAndre
Ross (PREP Student): Investigating complement regulation
in the lung.
Molly Smithers (Graduate
Student): Investigating the role of SP-A in regulating
complement mediated phagocytosis.
Kristi Williams (Assistant Research Professor): Investigating
the role of the CATERPILLER protein Monarch-1 in regulating
lung inflammation.
David Zaas M.D. (Fellow): Investigating
mechanisms of virulence of Pseudomonas aeruginosa. |