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Duke University




Duke Medical Center



Tim Oliver, Ph.D.

Associate Research Professor, Cell Biology

Director of Imaging










Confocal Information and Reservations

E-mail t.oliver@cellbio.duke.edu

337 Nanaline Duke Building
Duke Box 3709
Durham, NC 27710

Telephone
919-681-4076
Fax 919-681-4190


Selected Publications
Geunes-Boyer S.  Oliver T. N., Janbon G., Lodge J. K., Heitman J., Perfect J. R. and Wright, J. R. 2009 Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival. Infection and Immunity 77,7, 2783-2794. -PDF-

Oliver, T 2009. Distinguishing the data from the dark: Single source software or microscopy mix and match? Microscopy Today 17 (3): 38-42. Reproduced with editorial permission of Microscopy Today. -PDF-

Oldham M,  Sakhalkar H, Oliver T, Allan Johnson G and Dewhirst M 2008. Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography. Journal of Biomedical Optics 13 (2): 021113-8. -PDF-

Coveney D, Cool J, Oliver T, and Capel B (2008). Four-dimensional analysis of vascularization during primary development of an organ, the gonad. PNAS 105 (20): 7212-7217. (Cover Story) -PDF-

Wang Q-Q, Li H, Oliver T, Glogauer M, Guo J, and He Y-W (2008). Integrin β1Regulates Phagosome Maturation in Macrophages through Rac Expression. The Journal of Immunology 180: 2419–2428. -PDF-

Henry SC, Daniell, X, Indaram, M, Whitesides, JF, Sempowski, GD, Howell D, Oliver T, and Taylor GA (2007). Impaired Macrophage Function Underscores Susceptibility to Salmonella in Mice Lacking Irgm1 (LRG-47). The Journal of
Immunology 179: 6963– 6972. -PDF-

Wu M, Kwon HY, Rattis F, Blum J, Zhao C, Ashkenazi R, Jackson T L, Gaiano N., Oliver T, and Reya, T. (2007) Imaging Hematopoietic Precursor Division in Real Time. Cell Stem Cell, Vol 1: 541-554 -PDF-

Sakhalkar HS, Dewhirst M, Oliver T, Cao Y and Oldham M (2007)Functional imaging in bulk tissue specimens using optical emission tomography: fluorescence
preservation during optical clearing.
Phys. Med. Biol. 52: 2035–2054. -PDF-

Oldham M, Sakhalkar H, Wang YM, Oliver T, Bentley R, Vujaskovic Z, Dewhirst M (2007). Three-dimensional imaging of whole rodent organs using optical computed and emission tomography.
J. Biomedical Optics 12 (1): 014009-1 to 014009-1. -PDF-

Zhou X, Babu JR, da Silva S. Shu Q, Graef IA, Oliver T, Tomoda T, Tani T, Wooten MW, and Wang F (2007). Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons PNAS 104 (14): 5842-5847.-PDF-

Mi Z, Oliver T, Guo, H, Gao C, and Kuo PC (2007) Thrombin-Cleaved COOH-Terminal Osteopontin Peptide Binds with Cyclophilin C to CD147 in Murine Breast Cancer Cells. Cancer Research 67 (9): 4088-4097. -PDF-

Eblaghie, M., Reedy, M., Oliver, T.,   Mishina, Y. and Hogan B.L.M.. (2006). Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and behavior of distal lung epithelial cells. Dev. Biology 291: 67-82. -PDF-

Li H., Oliver T., Jia W. and   He Y. (2006) Efficient dendritic cell priming of T lymphocytes depends on the extracellular matrix protein mindin. The EMBO Journal online 25: 4097-4107, oi:10.1038/sj.emboj.7601289. -PDF-

Oldham M., Sakhalkar, H., Oliver. T., Wang, Y.M.   Kirpatrick, J., Yiting C., Badea C. and Johnson G. A. (2006). Three-dimensional imaging of xenograft tumors using optical computed   and emission tomography. Med. Phys. 33 (9): 3193-3202. -PDF-

Burton, E. A., Oliver, T.N. and Pendergast A.(2005) Abl Kinases Regulate Actin Comet Tail Elongation via an   N-WASP-Dependent Pathway. Molecular and Cellular Biology 25
(20): 8834-8843. -PDF-

Price T.M, Hansen E.L, Oliver T.N. (2005). Immunofluorescent localization of a novel progesterone receptor(s) in a T47D-Y breast cancer cell line lacking genomic progesterone receptor expression. J Soc Gynecol Investig. 12(8): 610-6. -PDF-

Liu Y, Stein E., Oliver T, Li Y., Brunken W. J, Koch M, Tessier-Lavigne M, and Hogan B.L.M. (2004) Novel Role for Netrins in Regulating Epithelial Behavior during Lung Branching Morphogenesis. Current Biology 14 (10
): 897-905 -PDF-

Pline WA, Edmisten KL, Oliver T, Wilcut
JW,  Wells R and  Allen NS (2002). Use of digital image analysis, viability stains, and germination assays to estimate conventional and glyphosate-resistant cotton pollen viability. Crop Science 42: 2193-2200. (Cover Story) -PDF-

Pletjushkina O.J., Rajfur Z.,Pomorski P., Oliver T.N., Vasiliev J.M. and Jacobson K.A. (2001) Induction of cortical oscillations by depolymerization of microtubules: Interplay of calcium and rho-mediated contractility Cell Motil. Cytoskeleton 48(4): 235-44. -PDF-

Oliver, T.N., Berg J.S. and Cheney, R.E. (1999) Tails of Unconventional Myosins. Cell and Molecular Life Sciences 56: 243-257. -PDF-

Oliver, T.N., Dembo, M. and Jacobson, K. (1999). Separation of Propulsive and Adhesive Traction Stresses in Locomoting Keratocytes. J. Cell Biol. 145: 589-604. -PDF-

Oliver, T.N., Dembo, M. and Jacobson, K. (1998). Design and use of   substrata to measure traction forces generated by cultured cells. Methods in Enzymology: Molecular Motors and the Cytoskeleton 298: 497-521. -PDF-

Pletjushkina, O.Y., Belkin A.M., Ivanova, O.Y., Oliver T.N., Vasiliev, J.M. and Jacobson, K. (1998). Maturation of Cell-Substratum Focal Adhesions Induced by Depolymerization of Microtubules is Mediated by Increased Cortical Tension. Cell Adhesion and Communication 5: 121-135. -PDF-

Dembo, M., Oliver, T.N., Ishihara, A. and Jacobson, K. (1996). Imaging the Traction Stresses Exerted by Locomoting Cells with the Elastic Substratum Method. Biophysical J. 70: 2008-2022. -PDF-

Oliver, T.N., Dembo, M. and Jacobson, K. (1995). Traction Forces in Locomoting Cells (with videotape supplement). Cell Motility and the Cystoskeleton 31: 225-240. -PDF-

Kenworthy, A.K., Magid, A.D., Oliver, T.N. and McIntosh, T.J. (1994). Colloid Osmotic Pressure and Structure of Alpha-Crystallins from Steer Crystallins. Exp. Eye Research 59
: 11-30. -PDF-

Lee, J., Leonard, M., Oliver, T., Ishihara, A. and Jacobson, K. (1994). Traction Forces Generated by Locomoting Keratocytes. J. Cell Biol. 127 (6): 1957-64. -PDF-

Oliver, T., Lee, J. and Jacobson, K. (1994) Forces Exerted by Locomoting Cells. Seminars in Cell Biology 5: 139-147. -PDF-

Costello, M.J., Oliver, T.N. and Cobo, L.M.(1992) Cellular Architecture in Age-Related Human Nuclear Cataracts. IOVS 33: 3209-27. -PDF-

Misra, M., Taylor, D., Oliver, T.N. and Taylor, K. (1991) Effect of Organic Anions on the Crystallization of the Ca2+-ATPase of Muscle Sarcoplasmic Reticulum. Biochem. Biophys. Acta. 1077: 107-108. -PDF-

Olsen, I., Oliver, T., Muir, H., Smith, R. and Partridge, T.(1986)   Role of Cell Adhesion in Contact-Dependent Transfer of a Lysosomal Enzyme from Lymphocytes to Fibroblasts. J. Cell Sci. 85: 231-244. -PD
F-

Fox, B., Bull, T., and Oliver T.N.(1983) The Distribution and Assessment of Electron Microscopic Abnormalities of Human Cilia. Eur. J. Resp. Dis. 64 (127): 11-18. -PDF-

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