Clonally dominant cardiomyocytes direct heart morphogenesis.
Thursday, April 26, 2012
Nature 2012
As vertebrate embryos develop to adulthood, their organs undergo marked changes in size and tissue architecture. The heart acquires muscle mass and matures structurally to fulfil
Regeneration of Amputated Zebrafish Fin Rays from De Novo Osteoblasts
Monday, April 16, 2012
Developmental Cell 2012
Determining the cellular source of new skeletal elements is critical for understanding appendage regeneration in amphibians and fish. Recent lineage-tracing studies indicated
Sexually dimorphic fin regeneration in zebrafish controlled by androgen/GSK3 signaling.
Tuesday, November 22, 2011
Current Biology 2011
Certain fish and amphibians regenerate entire fins and limbs after amputation, whereas such potential is absent in birds and limited in mammals to digit tips [1, 2].
The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion
July 13, 2011
Development 2011
Natural models of heart regeneration in lower vertebrates such as zebrafish are based on invasive surgeries causing mechanical injuries that are limited in size. Here, we created a