Recent Publications

Yao, H., DiNapoli, L., and Capel, B. Meiotic Germ Cells Antagonize Mesonepheric Cell Migration and Testis Cord Formation. Development, (in press).

Brennan, J., Tilmann, C., Yao, H, and Capel, B. Pdgfr a mediates testis cord organization and fetal Leydig cell development in the XY gonad. Genes and Development, 17:800-810 (2003). <PDF>

Schmahl, J. and Capel, B. Cell proliferation is necessary for the determination of male fate in the gonad. Developmental Biology, 258: 264-76 (2003). <PDF>

Yao HH, Capel B. Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis. Dev Biol. 2002 Jun 15;246(2):356-65. <PDF>

Yao HH, Whoriskey W, Capel B. Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. Genes Dev. 2002 Jun 1;16(11):1433-40 <PDF>

Tilmann C, Capel B. Cellular and molecular pathways regulating mammalian sex determination. Recent Prog Horm Res. 2002;57:1-18. Review. <PDF>

Yao HH, Tilmann C, Zhao GQ, Capel B. The battle of the sexes: opposing pathways in sex determination. Novartis Found Symp. 2002;244:187-98; discussion 198-206, 253-7. <PDF>

Brennan J, Karl J, Capel B. Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad. Dev Biol. 2002 Apr 15;244(2):418-28. <PDF>

Colvin JS, Green RP, Schmahl J, Capel B, Ornitz DM. Male-to-female sex reversal in mice lacking fibroblast growth factor 9. Cell. 2001 Mar 23;104(6):875-89. <PDF>

Albrecht, K., Capel, B., Washburn, L.L., Eicher, E.M. Abnormal mesonephric cell migration in C57BL/6J-YMus domesticus fetal gonads. Dev Biol. 2000 Sep 1;225(1):26-36. <PDF>

Capel, B. The battle of the sexes. Mechanisms of Development, 92: 89-103 (2000). <PDF>

Schmahl, J, Eicher, E.M., Washburn, L.L. and Capel, B. Sry induces cell proliferation in the mouse gonad. Development, 127: 65-73 (2000). <PDF>

Tilmann, C. and Capel, B. Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad. Development 126: 2883-2890 (1999). <PDF>

Capel, B., Albrecht, K.H., Washburn, L. and Eicher, E.M. Migration of mesonephric cells into the mammalian gonad depends on Sry. Mechanisms of Development 84: 127-131 (1999). <PDF>

Capel, B. Sex in the 90s: SRY and the Switch to the Male Pathway. Annu. Rev. Physiol. 1998. 60:497-523. <PDF>

Brennan J, Karl J, Martineau J, Nordqvist K, Schmahl J, Tilmann C, Ung K, Capel, B. Sry and the testis: molecular pathways of organogenesis. J Exp Zool. 1998 Aug 1;281(5):494-500. <PDF>

Karl, J. and Capel, B. Sertoli cells of the mouse testis originate from the coelomic epithelium. Developmental Biology 203: 323-333 (1998). <PDF>