Recent Publications

Schmahl, J., Kim, Y, Colvin, J.S., Ornitz, D.M. and Capel, B. Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development 131: 3627-3635 (2004). <PDF>

Brennan, J and Capel, B. One Tissue, Two Fates: Molelcular genetic events that underlie testis versus ovary development. Nature Reviews Genetics 5: 509-521 (2004). <PDF>

Yao, H., DiNapoli, L., and Capel, B. Meiotic germ cells antagonize mesonepheric cell migration and testis cord formation. Development 130: 5895-5902 (2003). <PDF>

Brennan, J., Tilmann, C., Yao, H, and Capel, B. Pdgfr a mediates testis cord organization and fetal Leydig cell development in the XY gonad. Genes and Development, 17:800-810 (2003). <PDF>

Schmahl, J. and Capel, B. Cell proliferation is necessary for the determination of male fate in the gonad. Developmental Biology, 258: 264-76 (2003). <PDF>

Yao HH, Capel B. Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis. Dev Biol. 2002 Jun 15;246(2):356-65. <PDF>

Yao HH, Whoriskey W, Capel B. Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. Genes Dev. 2002 Jun 1;16(11):1433-40 <PDF>

Tilmann C, Capel B. Cellular and molecular pathways regulating mammalian sex determination. Recent Prog Horm Res. 2002;57:1-18. Review. <PDF>

Yao HH, Tilmann C, Zhao GQ, Capel B. The battle of the sexes: opposing pathways in sex determination. Novartis Found Symp. 2002;244:187-98; discussion 198-206, 253-7. <PDF>

Brennan J, Karl J, Capel B. Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad. Dev Biol. 2002 Apr 15;244(2):418-28. <PDF>

Colvin JS, Green RP, Schmahl J, Capel B, Ornitz DM. Male-to-female sex reversal in mice lacking fibroblast growth factor 9. Cell. 2001 Mar 23;104(6):875-89. <PDF>

Albrecht, K., Capel, B., Washburn, L.L., Eicher, E.M. Abnormal mesonephric cell migration in C57BL/6J-YMus domesticus fetal gonads. Dev Biol. 2000 Sep 1;225(1):26-36. <PDF>

Capel, B. The battle of the sexes. Mechanisms of Development, 92: 89-103 (2000). <PDF>

Schmahl, J, Eicher, E.M., Washburn, L.L. and Capel, B. Sry induces cell proliferation in the mouse gonad. Development, 127: 65-73 (2000). <PDF>

Tilmann, C. and Capel, B. Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad. Development 126: 2883-2890 (1999). <PDF>

Capel, B., Albrecht, K.H., Washburn, L. and Eicher, E.M. Migration of mesonephric cells into the mammalian gonad depends on Sry. Mechanisms of Development 84: 127-131 (1999). <PDF>

Capel, B. Sex in the 90s: SRY and the Switch to the Male Pathway. Annu. Rev. Physiol. 1998. 60:497-523. <PDF>

Brennan J, Karl J, Martineau J, Nordqvist K, Schmahl J, Tilmann C, Ung K, Capel, B. Sry and the testis: molecular pathways of organogenesis. J Exp Zool. 1998 Aug 1;281(5):494-500. <PDF>

Karl, J. and Capel, B. Sertoli cells of the mouse testis originate from the coelomic epithelium. Developmental Biology 203: 323-333 (1998). <PDF>