Education:
University of Michigan (1997)
Ann Arbor, Michigan
B.S. - Neuroscience
University of Michigan (2008)
Ann Arbor, Michigan
PhD - Neuroscience
Research Interests:
Genetics of Neuroscience
Selected Publications:
Wong SC*, Oh E*, Ng CH, Lam KP (2003). Impaired germinal center formation and recall T-cell dependent immune responses in mice lacking the co-stimulatory ligand B7-H2. response. Blood 102: 1481-8.
*These authors contributed equally to the work
Yoshida S, Mears AJ, Friedman JS, Carter T, He S, Oh E, Jing Y, Farjo R, Fleury G, Barlow C, Hero AO, Swaroop A. (2004). Expression
profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl. Hum Mol Genet 13: 1487-503.
Cheng H, Khanna H, Oh EC, Hicks D, Mitton KP, Swaroop A. (2004). Photoreceptor-specific nuclear receptor NR2E3 functions as a
transcriptional activator in rod photoreceptors. Hum Mol Genet 13:
1563-75.
Akimoto M, Cheng H, Zhu D, Brzezinski JA, Khanna R, Filippova E, Oh EC, Jing Y, Linares J, Zareparsi S, Mears AJ, Hero A, Glaser T,
Swaroop A. (2006). Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors. Proc Natl Acad Sci USA 103: 3890-5.
Oh EC, Khan N, Novelli E, Khanna H, Strettoi E, Swaroop A. (2007). Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL. Proc Natl Acad Sci USA 104: 1679-84. Cover Image and Note: paper featured in ?In this
issue? section and ?Research Highlight? section of Nature Reviews
Neuroscience 8: 166-167.
Raven MA, Oh EC, Swaroop A, Reese BE. (2007). Afferent control of horizontal cell morphology revealed by genetic respecification of rods and cones. J Neurosci 27: 3540-7.
Oh EC, Cheng H, Hao H, Jia L, Khan N, Swaroop A. (2008). NRL directs the suppression of cone photoreceptor development through
activation of NR2E3. Brain Res 1236: 16-29.
Layman WS, McEwen DP, Beyer LA, Lalani SR, Fernbach SD, Oh E, Swaroop A, Hegg CC, Raphael Y, Martens JR, Martin DM. (2009). Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome. Hum Mol Genet. 18(11): 1909-23.
Jia L, Oh EC, Ng L, Srinvas, Kjellstrom S, Bush R, Swaroop A, Forrest D. (2009). Retinoid-related orphan nuclear receptor RORβ
is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci USA. 106(41): 17534-9.
Wiens CJ, Tong Y, Esmail MA, Oh EC, Gerdes JM, Rattner JB, Katsanis N, Park HW, Leroux MR. (2010). The Bardet-Biedl
syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate to modulate structure and function of the primary cilium. J Biol Chem 2010 Mar 5. [Epub ahead of print].
Neale BM, Fagerness J, Reynolds R, Sobrin L, Raychaudhuri S, Parker M, Tan P, Oh EC, Merriam JE, Souied E, Bernstein PS, Zhang K,
Zack DJ, Campochiaro B, Campochiaro P, Ripke S, Smith RT, Barile GR, Katsanis N, Allikmets R, Daly MJ, Seddon JM. (2010). A genome-wide scan of advanced age-related macular degeneration suggests a novel
role of Lipase-C. Accepted at Proc Natl Acad Sci USA.
Oh EC and Katsanis N. (2010). Cilia in vertebrate development and disease. Accepted at Development.
Hayashi-Takagi A, Oh EC, Nwulia E, Katsanis N, Sawa A. (2010). Major susceptibility genes for schizophrenia: biology, interactions and roles in disease pathogenesis. Accepted at Mol Psychiatry.
